Novo Nordisk says Alzheimer's drug trial fails to meet main goal - SnS MAG

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Monday, November 24, 2025

Novo Nordisk says Alzheimer's drug trial fails to meet main goal

Novo Nordisk says Alzheimer's drug trial fails to meet main goal

COPENHAGEN (Reuters) -Novo Nordisk said on Monday ​an older oral version of ‌its semaglutide drug failed to meet its main ‌goal in late-stage trials testing whether the medicine can slow cognitive decline in Alzheimer's patients.

The ⁠data is key ‌for Novo because Alzheimer's disease would be a large ‍new market for GLP-1 medicines like semaglutide after blockbuster success in the treatment of ​obesity and diabetes. Alzheimer'‌s patients currently have limited treatment options.

The drug being tested is Novo's Rybelsus, a pill currently approved only for treatment of type ⁠2 diabetes. Both ​Rybelsus and Novo'​s blockbuster drugs Ozempic and Wegovy are based on the same ‍active ingredient,⁠ semaglutide, a GLP-1 medicine.

(Writing by Stine ⁠Jacobsen and Maggie Fick; Editing by ‌Jan Harvey, Terje Solsvik ‌and Anna Ringstrom)